Adults over age 65 are one of the most important populations for Covid-19 vaccination, so all the companies are testing their

Author : greensameblue

Publish Date : 2021-01-09 16:08:12

If I’m over 65, will it be safe to get the vaccine and will it actually work for me?

Adults over age 65 are one of the most important populations for Covid-19 vaccination, so all the companies are testing their vaccine in older adults. In fact, older adults are among those groups deemed high-priority for vaccination by the CDC.

Early data from the AstraZeneca vaccine actually show that older adults experienced fewer side effects than younger adults, and the vaccine was equally effective across all adult age groups. After vaccines have received an EUA or approval from the FDA, the CDC will determine which populations each vaccine is recommended for. There will likely be vaccines approved specifically for older adults.

Q: If I have an autoimmune disorder, will the vaccine be safe for me to get?

The simplest answer is that we don’t know yet, Hamburg said. Novavax is the only company so far to exclude people with autoimmune conditions from its trials, but that doesn’t mean there’s enough data on autoimmune people in other trials to draw conclusions about safety or effectiveness yet. When the CDC issues its recommendations, it will specifically state whether people with certain conditions should not get the vaccine.

Q: Will the vaccine be safe for people with diabetes, HIV, high blood pressure, or other underlying conditions to get?

This answer is not yet available either, but there’s a higher likelihood we’ll find out soon. Most of the phase 3 trials allowed participants to enroll if they had diabetes, HIV, kidney disease, liver disease, and most other chronic conditions, so it’s a matter of how many people with each of these conditions were in the trial and whether it’s enough to assess the safety and effectiveness. Again, the CDC will note in its recommendations whether people with certain conditions should not get certain vaccines.

Q: Will the vaccine be safe and effective for people undergoing cancer treatments, taking immunosuppressant drugs, or otherwise immunocompromised?

People in this group are in the same place as those who are pregnant: They were excluded from nearly every phase 3 trial except the Janssen studies, so we don’t have the data to know one way or another about the safety and effectiveness. Moss said he doesn’t anticipate any safety problems, and most non-live vaccines are safe for immunocompromised people to get. The bigger question is whether a vaccine would work for this group. The definition of immunosuppression is an immune system that doesn’t function at 100%, so it may not respond well enough to the vaccine to offer protection. We won’t know until researchers have gathered more data in future clinical trials or from observational trials in the general population.

Q: How do I know the vaccine will be safe for me if I’m Black or Latinx or otherwise not white?

Historically, clinical trials have not enrolled enough Black, Latinx, and other nonwhite groups, resulting in data that may or may not apply to those groups. For example, the human papillomavirus (HPV) vaccine trials did not include enough Black women, and researchers learned later that the HPV strains covered by the vaccine are most common in white women, but not in Black women. Also historically, Black people, in particular, have repeatedly been exploited and abused by the U.S. medical system, so it’s understandable why Black people may be especially leery of getting a Covid-19 vaccine.

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