A review by US regulators of the single-shot Johnson & Johnson coronavirus vaccine has found it is safe and effective.

It paves the way for it to become the third Covid-19 vaccine to be authorised in the US, possibly within days.

The vaccine would be a cost-effective alternative to the Pfizer and Moderna vaccines, and can be stored in a refrigerator instead of a freezer.

Results from trials were released by Johnson & Johnson last month.

The Belgian company Janssen, which is owned by the pharmaceutical giant, said its data showed the product was highly effective against severe disease.

It comes as Ghana became the first country to receive coronavirus vaccines through the Covax vaccine-sharing initiative.

The briefing document published by the US Food and Drug Administration (FDA) gives more detail on the data submitted by Janssen to the regulator. The FDA concludes that the Johnson & Johnson vaccine has "known benefits" in reducing both symptomatic and severe illness.

Results from vaccine trials conducted in the US, South Africa and Brazil found its efficacy against the worst outcomes of the virus was "similarly high" but overall protection was lower in South Africa and Brazil, where virus variants have become dominant.

Data showed it was more than 85% effective at preventing serious illness, but only 66% effective overall, when moderate cases were included, when considering cases at least 28 days after vaccination.

• US passes 500,000 deaths to Covid

Notably, there were no deaths among participants who had received the vaccine and no hospital admissions after 28 days post-vaccine.

An external committee of experts will meet on Friday to recommend whether the FDA should authorise the vaccine, possibly adding to a coming surge in vaccine availability in the US.

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A White House official said the administration anticipated distributing at least three million doses of the Johnson & Johnson vaccine next week, should it receive emergency authorisation from the FDA.

The company says it plans to deliver 20 million doses in total by late March, in line with an agreement to supply the US with 100m doses by the end of June.

Which countries have ordered the Johnson & Johnson jab?

• UK - 30m doses
• EU - 200m doses
• Canada - 38m doses
• Covax nations - 500m doses

Global vaccine rollout

Enter a country or territory to find out the progress of the vaccine rollout

Type in 2 or more characters for results.

 

 

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Not only will the vaccine require fewer doses than its two-shot Pfizer and Moderna counterparts, it will also require fewer vaccine appointments and medical staff as a result.

Over 65 million Americans have already been vaccinated and about 1.3 million doses are being administered across the country each day.

New cases, hospitalisations and deaths from Covid-19 in the US have all been on the decline over the past few weeks.

Top public health experts, however, continue to warn that mutations of the virus can still threaten progress.

When did you first text 'coronavirus'?

About a year ago, the pandemic hit. We're asking you to search through old text messages and find the first time the term coronavirus (corona or Covid) came up in your conversations. Send us the exchange.

What do you remember from then? What were you feeling? At the time, did you first realise it was going to be life-altering?

Please tell us in the form below or email us at [email protected], if you can't view the form.

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