Moderna vaccines use an mRNA platform, all they need to do to tweak the vaccine is swap out the genetic code so

Author : torunlota

Publish Date : 2021-01-09 18:26:13

Moderna vaccines use an mRNA platform, all they need to do to tweak the vaccine is swap out the genetic code so

Epic Games, bestWill the current vaccines protect against the new Covid strains scientists have discovered?
In recent weeks, much Covid reporting has focused on two new variants of the SARS-CoV-2 coronavirus: one, called B.1.1.7, appears to have originated in the United Kingdom and the other, 501Y.V2, in South Africa. Though a study last August concluded that Covid vaccine candidates “would likely match all currently circulating variants,” the big question now is whether the two authorized vaccines, or any vaccines currently in trials, will protect against these brand new variants.
The South African variant raises more concerns than the UK one because of where its mutations occur. In mid-December, vaccine manufacturers had already begun studying whether their vaccines would work on the new variants. Scientists don’t have a firm answer, yet but the most recent data suggests some optimism. A small study by Pfizer and scientists at the University of Texas Medical Branch showed that the Pfizer vaccine seems to work against both new variants. However, the study is small and not yet peer-reviewed. Moderna has not yet published any data about the new variants and its vaccine.
It’s important to note that these kinds of mutations were not unexpected. All viruses mutate, the coronavirus has already mutated thousands of times, and scientists, including vaccine developers, expect it to continue mutating. What matters is how much it mutates and where those mutations occur. Current vaccines target the spike protein, which has already accumulated about 4000 mutations. These haven’t affected the vaccine’s effectiveness because current vaccines target multiple parts of the spike protein. It would take major changes to affect how well the vaccine works, and those are unlikely to happen soon, as University of Texas Medical Branch researcher Vineet Menachery told Vox.
Further, even if the mutations do affect current vaccines’ effectiveness, it doesn’t mean the vaccine would suddenly become useless. It may become less than 95% effective, but it would still offer some protection. If the coronavirus ever mutates so much that the vaccine becomes very ineffective, it wouldn’t require a whole other year to develop a new vaccine either. Since the Pfizer and Moderna vaccines use an mRNA platform, all they need to do to tweak the vaccine is swap out the genetic code so that it instructs cells to create a spike protein like those on the new variants. The downside is that it might mean another round of vaccinations, but for now, that still appears to be a problem in the future, not the present. We’ll update this question as we learn more.
To be sure, plenty of higher-end malls will survive and even thrive as the pandemic lifts and cooped-up consumers rediscover in-person shopping — especially when it’s paired with food

and entertainment that deliver a real experience. That’s one reason the Mall of America, an ur-destination for shopping-as-experience, was recently able to rework its mortgage deal with lenders. This vision of an all-in-one megamall is what drives the likes of the phantasmagoric American Dream in East Rutherford, New Jersey, which boasts both a Nickelodeon Universe theme park and a DreamWorks Water Park.
But for weaker malls, it’s time to face reality: The shopping habits that built this singular sector have changed for good. A long-overdue shakeout is happening, and it can’t be survived with tweaks to the same old formulas. One way or another, lots of malls need to stop being malls.

Category : general

common: The case conversion pipes no longer let falsy values through. They now map both null and undefined to null and r

Moderna vaccines use an mRNA platform, all they need to do to tweak the vaccine is swap out the genetic code so

common: The case conversion pipes no longer let falsy values through. They now map both null and undefined to null and r

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