The current vaccines have been shown definitively in clinical trials to prevent severe symptomatic COVID-19 disease incredibly well. We do not yet know if they prevent infection or spread.
Moderna Vaccine Trial Results:
Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, Diemert D, Spector SA, Rouphael N, Creech CB, McGettigan J, Kehtan S, Segall N, Solis J, Brosz A, Fierro C, Schwartz H, Neuzil K, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Mascola J, Polakowski L, Ledgerwood J, Graham BS, Bennett H, Pajon R, Knightly C, Leav B, Deng W, Zhou H, Han S, Ivarsson M, Miller J, Zaks T; COVE Study Group. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2020 Dec 30:NEJMoa2035389. doi: 10.1056/NEJMoa2035389. Epub ahead of print. PMID: 33378609; PMCID: PMC7787219. https://www.nejm.org/doi/10.1056/NEJMoa2035389
Pfizer Vaccine Trial Results:
Polack FP, Thomas SJ, Kitchin N, Absalon J, Gurtman A, Lockhart S, Perez JL, Pérez Marc G, Moreira ED, Zerbini C, Bailey R, Swanson KA, Roychoudhury S, Koury K, Li P, Kalina WV, Cooper D, Frenck RW Jr, Hammitt LL, Türeci Ö, Nell H, Schaefer A, Ünal S, Tresnan DB, Mather S, Dormitzer PR, Şahin U, Jansen KU, Gruber WC; C4591001 Clinical Trial Group. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. N Engl J Med. 2020 Dec 31;383(27):2603–2615. doi: 10.1056/NEJMoa2034577. Epub 2020 Dec 10. PMID: 33301246; PMCID: PMC7745181. https://www.nejm.org/doi/10.1056/NEJMoa2034577
AstraZeneca and Oxford University Trial Results:
Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL, Barnabas SL, Bhorat QE, Bibi S, Briner C, Cicconi P, Collins AM, Colin-Jones R, Cutland CL, Darton TC, Dheda K, Duncan CJA, Emary KRW, Ewer KJ, Fairlie L, Faust SN, Feng S, Ferreira DM, Finn A, Goodman AL, Green CM, Green CA, Heath PT, Hill C, Hill H, Hirsch I, Hodgson SHC, Izu A, Jackson S, Jenkin D, Joe CCD, Kerridge S, Koen A, Kwatra G, Lazarus R, Lawrie AM, Lelliott A, Libri V, Lillie PJ, Mallory R, Mendes AVA, Milan EP, Minassian AM, McGregor A, Morrison H, Mujadidi YF, Nana A, O’Reilly PJ, Padayachee SD, Pittella A, Plested E, Pollock KM, Ramasamy MN, Rhead S, Schwarzbold AV, Singh N, Smith A, Song R, Snape MD, Sprinz E, Sutherland RK, Tarrant R, Thomson EC, Török ME, Toshner M, Turner DPJ, Vekemans J, Villafana TL, Watson MEE, Williams CJ, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ; Oxford COVID Vaccine Trial Group. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. Lancet. 2021 Jan 9;397(10269):99–111. doi: 10.1016/S0140–6736(20)32661–1. Epub 2020 Dec 8. Erratum in: Lancet. 2021 Jan 9;397(10269):98. PMID: 33306989; PMCID: PMC7723445She repeats her routine daily, growing more and more disheartened with her current circumstances. Three weeks later, she misses a crucial deadline: her period. After twenty-three failed calls to her former client, she resigns to take a new job as a professional single mother over 35.
The Obama Chair patiently waits for Harry to finish his tirade, which long experience suggests will build to a rage and end suddenly when he passes out.
HARRY:(cont.) (confidentially) When I was a cop the only people who had my back? The GOP. They promised to sweep those process parading scumbags from office, and now, when this orange faced parody of a bad TV show sells the country to Russia what do they scream? ‘You didn’t involve his lawyers, didn’t do the hearings right, didn’t out the whistle blower.’
He leans over the arm of his recliner to make eye contact with Obama Chair.
HARRY:(cont.) In my day we called them Confidential Informants.
Harry sweeps his long legs over the footrest and carts the empty bottle to the kitchen, which is a typing desk with a George Foreman grill. Underneath he’s stacked a half empty case of James Brooks on top of a case of Alpo.
The Sam’s Club price label still affixed to both cases.
Harry tosses the empty into his industrial waste can and leans over to grab a fresh bottle. His back spasms. He grimaces and rubs it.
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