Le Ministère des travaux publics et du logement public

Author : ndoll96
Publish Date : 2021-03-12 08:09:01


Le Ministère des travaux publics et du logement public

Serang — Le Ministère des travaux publics et du logement public (PUPR) a commencé les préparatifs de la construction du tronçon 3 de la route à péage de 33 km Serang — Panimbang, section Cileles — Panimbang, marqué par la signature du contrat pour le lot de travaux de construction du Serang -Panimbang Section 3 Toll Road, qui est évalué à Rp. 4,5 billions entre le ministère PUPR et l’entrepreneur Sino Road and Bridge Group Co. Ltd, à l’Agence nationale de mise en œuvre des routes de Banten (BPJN), en présence de l’inspecteur général par intérim Widiarto, chef de l’Agence de réglementation des routes à péage, Danang Parikesit, président directeur de PT. Wijaya Karya (Tbk) Agung Budi Waskito et président directeur de PT. Adhi Karya (Tbk) Entus Asnawi M.

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Après la signature du contrat, le ministre du PUPR Basuki Hadimuljono a demandé à l’entrepreneur d’accélérer la construction du tronçon Cileles — Panimbang. Le gouvernement n’a pas de programme spécifique pour mener à bien le lancement de la construction de la route à péage.

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«Nous devons utiliser le style (rythme de travail) du ministère du PUPR qui est rapide. L’acquisition de terrains est prête à environ 78% sur 33 km, il n’y a donc aucune raison de retarder le développement. Il n’est pas nécessaire d’organiser une cérémonie d’inauguration, l’important est que nous puissions commencer et terminer la construction immédiatement », a déclaré le ministre Basuki.

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Le tronçon 3 du tronçon Cileles — Panimbang est la dernière partie du lot de travaux à péage de 83,67 km Serang-Panimbang. Dans l’ensemble, cette route à péage est divisée en 3 tronçons, à savoir le tronçon 1 du tronçon Serang — Rangkasbitung (26,50 km), le tronçon 2 du tronçon Rangkasbitung — Cileles (24,17 km) et le tronçon 3 du tronçon Cileles — Panimbang (33 km ). Pour la section 3, la partie BUJT est divisée en 55% détenue par Sino Road & Bridge Co. Ltd, chacune détenue à 22,5% par PT. Wijaya Karya (Tbk) et PT. Adhi Karya (Tbk).

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La construction de cette route à péage est réalisée dans le cadre du programme de partenariat public-privé (PPP) avec une valeur d’investissement de 5,33 billions de roupies constituée des sections 1 à 2, la partie des entités commerciales à péage (BUJT) par PT Wijaya Karya Serang Panimbang , tandis que la section 3 devient la partie du gouvernement dont l’objectif est de fonctionner pleinement en 2023. Actuellement, la progression du développement sur la section Serang — Rangkasbitung jusqu’en novembre 2020 a atteint 84,18%.

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A COVID-19 vaccine could come within weeks — at least a limited supply to front-line medical workers. Drug companies Pfizer, Moderna and AstraZeneca have the leading vaccine candidates. Several others remain in development.

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The Food and Drug Administration is responsible for authorizing and approving all vaccines in the USA. Widespread vaccine use once one is given the green light could provide a way to end the coronavirus pandemic. USA TODAY interviewed FDA Commissioner Stephen Hahn about how the approval process works, how quickly it could go, and how the agency will encourage Americans to take the vaccine.

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What is the ACIP? For a COVID-19 vaccine to get cleared by the FDA, these 15 experts will vouch for its safety
How a COVID-19 vaccine will be authorized
Question: How will a COVID-19 vaccine get clearance for use?

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Answer: Companies have the option of applying for either a license (called a Biologics License Application) or an Emergency Use Authorization. It’s their choice.

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Q: What is an Emergency Use Authorization (EUA)?
A: An Emergency Use Authorization is an authority that Congress gave to FDA after the 9/11 terrorist attacks to allow countermeasures, treatments or vaccines to be available earlier than would normally be done under the approval process.

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Q: Has the FDA ever issued an Emergency Use Authorization for a vaccine?
A: Yes, for an anthrax vaccine (in 2005).
Stephen Hahn, commissioner of the Food and Drug Administration, promises transparency in the vaccine approval process.

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How an Emergency Use Authorization differs from FDA approval
Q: What standards must companies meet to get Emergency Use Authorization?

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A: The standard that’s used for an EUA is that it must be effective in the treatment or prevention of COVID-19 and that the risk/benefit ratio is in favor of authorization.

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For vaccines, that’s especially important because unlike treatments, vaccines are given to people who are otherwise healthy. They don’t have COVID-19, so when we look into the risk/benefit ratio … we have to factor that into its safety and effectiveness. We have to be incredibly thoughtful about this.

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How FDA evaluates the safety of a vaccine given emergency authorization
Q: What can you say to reassure people that a vaccine approved under an EUA is just as safe and effective as one approved under a BLA, even though there isn’t as much long-term effectiveness data?

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A: The standards we expect in safety and effectiveness in an EUA are very similar to what we expect in a BLA. Our career scientists have been doing this for years; this is their area of expertise. They will be judging the science and medicine.

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A subject receives a shot in the first-stage safety trial of a potential vaccine by Moderna for COVID-19 at the Kaiser Permanente Washington Health Research Institute in Seattle on March 16.
Q: Will COVID-19 vaccines issued under an EUA continue in the licensing process and eventually be fully licensed using a Biologics License Application?

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A: Yes. Our expectation is that the sponsors (the vaccine companies) will submit an application, and it’s their call if it’s an EUA or a BLA. Then they would submit, subsequently or in real time, a BLA. We will, of course, prioritize the application for an Emergency Use Authorization, but we will then go through the normal reviews.

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How the FDA will encourage people to take the vaccine
Q: What more could be done to encourage people to take an authorized vaccine? Is there anything you can do as head of the FDA to encourage people to get vaccinated?

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A: I was a doctor before I became FDA commissioner. If you explain something to a patient — if you share that in a transparent way and then you do what you say you’re going to do — that builds trust. We will follow our process, look at the criteria — we’ll be transparent about those.

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Q: Will you get the vaccine yourself? Either in April or May when it may become available to the general public, or do you fit in one of the categories that are likely to have access sooner, such as front-line medical workers?

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A: I’ve been clear, I would not allow the agency to authorize or approve a vaccine that I wouldn’t want my own family to get. No one at FDA would want that to occur.
When it’s appropriate for me to get the vaccine, from the guidelines’ point of view, I will get that vaccine. I would strongly urge my family to get it. I have 100% confidence in the staff at FDA. If it would enhance confidence in the vaccine, I would get the vaccine as soon as it is authorized.

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Maria Harvey and her sister Ashley Makridakis protest mandatory flu vaccinations outside the Massachusetts Statehouse on Aug. 30 in Boston. Public health authorities say flu shots are very important this year to avoid overburdening the health system amid the coronavirus pandemic.
Q: An employer or school cannot require someone to get a vaccine issued under an EUA, right?

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A: Institutions may require individuals to take an FDA-approved vaccine or apply for an exception. However, EUA products are still considered investigational.

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It’s possible that some employers or schools will have questions or concerns about an investigational product issued an Emergency Use Authorization, which is why we will be as transparent as possible about the data and information we use to make our decision. This should help those organizations determine what is most appropriate for them.

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How long it will take for a vaccine to be authorized
There are several steps to the vaccine authorization process. First, a company must apply to the FDA. Then, the FDA must go through the application and send it to an outside review board called the Vaccines and Related Biological Products Advisory Committee (VRBPAC). That committee meets on Dec. 10 and will send the FDA its comments and recommendations. Only then can the FDA make a final decision on a vaccine.

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Q: How long should we expect FDA to deliberate after it hears from that committee?
A: We expect it to be days, but it’s very dependent on the complexity of the data and the comments we get back from VRBPAC.
Q: So it could be longer?

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A: We cannot prejudge our process; our scientists have to make the decision. We will take the time that’s needed to make the right call on this.
We want to move quickly because this is a national emergency, but we will make sure that our scientists take the time they need to make an appropriate decision. It is our job to get this right and make the correct decision regarding vaccine safety and efficacy.

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Staff members monitor patients at Stormont Vail Health on Nov. 18 in Topeka, Kan. The hospital has devoted an entire floor to COVID-19 patients.
Q: How much paperwork does an EUA involve? In the old days, there was so much paperwork, it came in on wooden pallets. Can you give us a metric?



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