The M is for messenger and RNA is the nucleic acid which is the key intermediary between DNA,

Author : fastitem123

Publish Date : 2021-01-07 18:45:13

The M is for messenger and RNA is the nucleic acid which is the key intermediary between DNA, our genetic code, and the formation of proteins, which make up the substance of our bodies. There’s never been an mRNA vaccine approved for general use. mRNA vaccines are extremely clever. They provide a blueprint — the mRNA — that gets into the cell and tricks it into creating the same spike protein that appears on the surface of the coronavirus, but there’s no virus. Then the body reacts and creates antibodies to that protein, so if the virus ever invades, the body is poised to attack infected cells which show the spike protein.
These vaccines look to be extraordinarily safe. About 2 million Americans have now been vaccinated and we’re only seeing a few reactions. The threat from Covid-19 is much, much greater than any possible threat of the vaccine itself, so the risk-benefit ratio right now looks to be pretty spectacular.

“I’m surprised that we’re in a third wave. I thought we would learn our lesson…I didn’t think that every area of this country would be in denial until they were overwhelmed.”
How did the richest country in the world become home to the worst outbreak of Covid-19 in the world? Is this a failure of traditional public health measures or is it something else?
This is a story that will be told and retold as a cautionary lesson. What’s obvious is that we did not have leadership from the top. We did not have a consistent public health message or a dependence on science. And we did not have anything remotely like a national strategy to combat anything. We saw it right from the beginning in the president’s downplaying of the virus’s seriousness, which he told Bob Woodward he knew to be false at the time. That was particularly shocking. In order to get people to do what they probably would not like to do — wear masks and stay away from other people — you need planning, and a consistent, rational justification from the top. We had none of that.
Instead, there was a tremendous amount of strife, controversy, and counter-messaging. Advisors told the president what he wanted to hear, advancing a bizarre idea that the more “low risk” people that got sick, the more we would be protected. It’s not a plan that could ever have worked. The failure at the top made it very difficult for others to build their own effective responses, even though most governors desperately tried. There was also a neutering and silencing of our main public health agency, the Centers for Disease Control.
I don’t think there was a failure of public health per se, but there has been a failure of investment in public health over decades. Prevention efforts have been repeatedly cut, including those around epidemic prevention. So our public health infrastructure was not up to the task. Even with ideal leadership from the top, we didn’t have the people, the things, the communication infrastructure — we had almost none of the pieces in sufficient volume to respond to this. I don’t want to call it a public health failure because everybody in public health was trying so hard; none of them failed. But when no resources are devoted to the infrastructure, it is completely predictable that the response to one of the great challenges of our generation would be inadequate.
How the U.S. Messed Up Covid-19 So Badly
Harvard social epidemiologist Nancy Krieger breaks down excess deaths and workplace safety findings
elemental.medium.com
2020 is the Year of the Pandemic. When we talked in March, where did you think we would be by the end of the year?
I’m surprised that we’re in a third wave. I thought we would learn our lesson. I thought that Ohio would learn from New York, and Indiana would learn from Ohio, and the Dakotas would learn from Indiana. I didn’t think that every area of this country would be in denial until they were overwhelmed. I thought back then that there would be more federal response once they actually realized the seriousness of this. So I am surprised that there hasn’t been a nationally coordinated response by now.
I also never saw coming the politicization of basic public health measures, that it would be seen as a weird badge of honor, or toughness, or machismo not to wear a mask and to engage in mass spreading behavior. It’s all contributed to this disaster.
I did see the potential for disaster if nothing much was done. I didn’t anticipate so little being done, and particularly that there would be so many people working to make it worse.
How does this end?
I think we’re at the beginning of that ending, but it’s going to be a long last chapter. It’s going to end in this country with a more coherent, integrated, coordinated public health response combined with more effective, and hopefully fair and just distribution of vaccines, as fast as we can get them out. I can’t quite see life getting back to normal on a national basis until sometime between June and September.
Even if it “ends” here, what will happen around the world, in India, in Africa, parts of Asia? That’s where we’re going to have to be looking and helping a huge amount.

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